av MB Lohse · 2013 · Citerat av 66 — Extensive searches of the known protein databases indicate that the According to the first, Wor3 evolved from an existing fungal domain or

Acts as transcriptional coactivator of estrogen and progesterone receptors (ESR1 and PGR) upon hormone activation. In presence of estrogen, binds to ESR1-responsive promoters. Required for YAP1 coactivation function on PGR activity. Synergizes with WBP2 in enhancing PGR activity (By similarity). Modulates expression of post-synaptic scaffolding proteins via regulation of ESR1, ESR2 and PGR

It was obtained from successive sequence analysis steps including similarity search, domain delineation, multiple sequence alignment and motif construction. 83054 non redundant protein sequences from SWISSPROT and PIR have been analysed yielding a database of 99058 domains Integrated search in PROSITE, Pfam, PRINTS and other family and domain databases. InterPro is a database of protein families, domains and functional sites in which identifiable features found in known proteins can be applied to unknown protein sequences. 1996-06-01 · 436 protein chains have been used for the construction of the domain database comprising a non-redundant set of proteins. Figure 1 shows the results of DIAL for a representative two-domain protein, α-transducin (PDB code: 1tad, A chain). 802 domains were initially identified by DIAL from the 436 protein chains which, after merging some conjoint clusters, leads to 695 domains (for merging, see DOMO is a database of aligned protein domains. It was obtained from successive sequence analysis steps including similarity search, domain delineation, multiple sequence alignment and motif construction.

Domain protein database

As such, it provides a broad survey of all known protein folds, detailed information about the close relatives of any particular protein, and a framework for future research and classification. Latest update on 2021-03-30 includes 68,237 non-redundant domains representing 758,470 protein structures. This resource is powered by the Protein Data Bank archive-information about the 3D shapes of proteins, nucleic acids, and complex assemblies that helps students and researchers understand all aspects of biomedicine and agriculture, from protein synthesis to health and disease. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data. Se hela listan på academic.oup.com FPbase is a moderated, user-editable fluorescent protein database designed by microscopists. Search, share, and organize information about fluorescent proteins and their characteristics.

The Pfam database is a large collection of protein families, each represented by multiple sequence alignments and hidden Markov models (HMMs). More Proteins are generally composed of one or more functional regions, commonly termed domains .

InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. We combine protein signatures from a number of member databases into a single searchable resource, capitalising on their individual strengths to produce a powerful integrated database and diagnostic tool.

Abstract. The Conserved Domain Architecture Retrieval Tool (CDART) performs similarity searches of the NCBI Entrez Protein Database based on domain

Each domain forms a compact folded three-dimensional structure. Many proteins consist of several domains. One domain may appear in a variety of different proteins. As such, it provides a broad survey of all known protein folds, detailed information about the close relatives of any particular protein, and a framework for future research and classification. Latest update on 2021-03-30 includes 68,237 non-redundant domains representing 758,470 protein structures. This resource is powered by the Protein Data Bank archive-information about the 3D shapes of proteins, nucleic acids, and complex assemblies that helps students and researchers understand all aspects of biomedicine and agriculture, from protein synthesis to health and disease. As a member of the wwPDB, the RCSB PDB curates and annotates PDB data.

Home; Analysis from RedoxiBase; Analysis from Input MOTILE SPERM DOMAIN CONTAINING PROTEIN 2 OCH INFLAMMATION.
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RNA; Complexes; Proteins GO_REF Any Gene Ontology Database references; REACTOME Any Reactome - a curated knowledgebase of protein sequences of SARS-CoV-2 globally available in the GISAID database Importantly, higher aa variations observed in the C-terminal domain (CTD) of av K Aripaka · 2019 · Citerat av 9 — Database analysis revealed a correlation between TRAF6 mRNA and Wnt which recruits Dishevelled protein to the intracellular domains.

For … Pfam protein domain database.

An evidence describes the source of an annotation, e.g. an experiment that has been published in the scientific literature, an orthologous protein, a record from another database, etc.

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This information is based on mapping of SMART genomic protein database to KEGG orthologous groups. Percentage points are related to the number of proteins with TIR domain which could be assigned to a KEGG orthologous group, and not all proteins containing TIR domain.

S Jayapalan, J av J Johansson · 2021 · Citerat av 1 — One method uses biomimetics in which the spider silk proteins (spidroins) (18−21) The terminal domains are unique to spidroins and regulate silk of a section of a repetitive region using the Zipper Database (ref (54)) for a Suparna Sanyal's laboratory studies mechanisms of protein synthesis and protein profile at the webpage of Disciplinary domain of Science and Technology, Here we provide a database on stop codon usage, covering more than 600 family "D" which is found in other multi-domain proteins. How could you use the Pfam database to suggest (guess) a possible (and very general) function for r 2005 Wiley-Liss, Inc. KEY WORDS: database; protein tyrosine kinase; protein serine-threonine kinase; kinase domain; families DATABASES: http://bioinf.uta.fi/ av E Raschperger · 2006 — domain containing proteins that serve as scaffolds, anchoring the expression. CLMP, which was identified through computer-based database searches, was. PhD position, Protein Structure and Bioinformatics, Dep. of Exp. Medical Science, Lund they affect less frequently the "gatekeeper" residue in the catalytic domain. Numerous databases containing information about DNA, RNA, and protein 25 juli 2002 — proteins to cells, tissues, organs, and gross anatomy. from genomics experiments in a different “domain” (e.g. the use of gene The SWISS-PROT Protein Knowledgebase is a curated protein sequence database that.